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  • Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation 

    Pavert, S.A. van de; Olivier, B.J.; Goverse, G.; Vondenhoff, M.F.R.; Greuter, M.J.; Beke, P.; Kusser, K.; Hopken, U.E.; Lipp, M.; Niederreither, K.; Blomhoff, R.; Sitnik, K.; Agace, W.W.; Randall, TD; Jonge, W.; Mebius, R.E. (2009)
    The location of embryonic lymph node development is determined by the initial clustering of lymphoid tissue-inducer (LTi) cells. Here we demonstrate that both the chemokine CXCL13 and the chemokine CCL21 attracted LTi cells ...