TY - JOUR
T1 - 1,5-Diphenyl-1,4-pentadiene-3-ones and cyclic analogues as antioxidative agents. Synthesis and structure-activity relationship.
AU - Sardjiman, S.S.
AU - Reksohadiprodjo, M.S.
AU - Hakim, L.
AU - van der Goot, H.
AU - Timmerman, H.
PY - 1997
Y1 - 1997
N2 - A series of 1,5-diphenyl-1,4-pentadiene-3-ones and cyclic analogues with OH-groups in the para position of the phenyl rings and various meta substituents were prepared and their antioxidant activity compared with that of curcumin. Most of them exhibited potent antioxidative activity, especially when all the meta positions were substituted by methoxy groups.
AB - A series of 1,5-diphenyl-1,4-pentadiene-3-ones and cyclic analogues with OH-groups in the para position of the phenyl rings and various meta substituents were prepared and their antioxidant activity compared with that of curcumin. Most of them exhibited potent antioxidative activity, especially when all the meta positions were substituted by methoxy groups.
U2 - 10.1016/S0223-5234(97)83288-6
DO - 10.1016/S0223-5234(97)83288-6
M3 - Article
SN - 0223-5234
VL - 32
SP - 625
EP - 630
JO - European Journal of Medicinal Chemistry
JF - European Journal of Medicinal Chemistry
ER -